I-KappaB Expression in Patient with Psoriasis Vulgaris

Abdelazeem, Nahed Omar; El Refaiee, Abdelaziz Abdel Salam; Othman, Shimaa Taha

doi:10.21608/ejmr.2022.231672

I-KappaB Expression in Patient with Psoriasis Vulgaris

Document Type : Original Article

Authors

¹ Dermatology department, Faculty of Medicine, Cairo University, Egypt

² Dermatology department, Faculty of Medicine, Beni-Suef University, Egypt

10.21608/ejmr.2022.231672

Abstract

The goal of this study is to measure serum level of I Kappa B in patients with psoriasis in comparison with healthy controls. 50 psoriatic patients and 40 age & gender matched apparently healthy controls were included in the study, patients were classified according to Psoriasis Area & Surface Index (PASI) score and serum samples for all participants were taken to measure I Kappa B level for each. The level of serum I Kappa B was found to be significantly lower in the patients (3.96 ±1.96) than in controls (11.02 ±2.22). This difference was of statistical significance (p-value =0.001).

Keywords

Main Subjects

Internal medicine ·

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