Efficacy Of High Flow Nasal Cannula Oxygenation In Acute Respiratory Failure Patients And Comparing With Noninvasive Positive Pressure Ventilation

Mohamed, Ahmed Shaban Ali; Yasin Mohamed, Ahmed

doi:10.21608/ejmr.2022.266288

Efficacy Of High Flow Nasal Cannula Oxygenation In Acute Respiratory Failure Patients And Comparing With Noninvasive Positive Pressure Ventilation

Document Type : Original Article

Authors

Critical care department, Faculty of Medicine, Beni-Suef University, Egypt

10.21608/ejmr.2022.266288

Abstract

The goal of this study is to assess HFNC oxygenation and compare the efficacy of high-flow nasal cannula (HFNC) to noninvasive ventilation (NIV) on oxygenation in patients with acute hypoxemic respiratory failure. The patients were randomly grouped into two groups, 20 in each group. Group 1: treated by high-flow nasal cannula (HFNC) and group 2: treated by non-invasive ventilation. There was a statistically significant difference regarding P_aO₂/FiO₂ at baseline and at the end (P-value < 0.001) in both groups indicating improvement of oxygenation in both groups. There was a statistically significant difference between the two groups regarding the P_aO₂ and P_aO₂/FiO₂ratio (P-value < 0.05) at the end of the trial however the degree of oxygenation improvement was significantly higher with NIV group. The conclusion of our study: the use of high flow nasal cannula is effective in improving oxygenation but NIV was superior to HFNC.

Keywords

Main Subjects

Internal medicine ·

References

Avdeev, S. N. (2012). Current guidelines for oxygen therapy in emergency care. Terapevticheskii arkhiv, 84(12), 108-114.
Buckley, T., Dudley, J., Eberhart, M., Goldstein, M., & Kallstrom, T. (2007). AARC clinical practice guideline: Oxygen therapy in the home or alternate site health care facility-2007 revision & update. Respiratory care, 52(8), 1063-1068.
Driscoll, B. R., L. S. Howard, J. Earis and V. Mak (2017). "BTS guideline for oxygen use in adults in healthcare and emergency settings." Thorax 72(Suppl 1): ii1.
Soni, N. and P. Williams (2008). "Positive pressure ventilation: what is the real cost?" BJA: British Journal of Anaesthesia 101(4): 446-457.
Nava, S., & Hill, N. (2009). Non-invasive ventilation in acute respiratory failure. The Lancet, 374(9685), 250-259.
Berg, K. M., Clardy, P., & Donnino, M. W. (2012). Noninvasive ventilation for acute respiratory failure: a review of the literature and current guidelines. Internal and emergency medicine, 7(6), 539-545.
Esteban, A., Ferguson, N. D., Meade, M. O., Frutos-Vivar, F., Apezteguia, C., Brochard, L., ... & Anzueto, A. (2008). Evolution of mechanical ventilation in response to clinical research. American journal of respiratory and critical care medicine, 177(2), 170-177.
Lee, C. C., Mankodi, D., Shaharyar, S., Ravindranathan, S., Danckers, M., Herscovici, P., ... & Ferrer, G. (2016). High flow nasal cannula versus conventional oxygen therapy and non-invasive ventilation in adults with acute hypoxemic respiratory failure: a systematic review. Respiratory medicine, 121, 100-108.
Vargas, F., Saint-Leger, M., Boyer, A., Bui, N. H., & Hilbert, G. (2015). Physiologic effects of high-flow nasal cannula oxygen in critical care subjects. Respiratory care 60(10): 1369-1376.
Schwabbauer, N., Berg, B., Blumenstock, G., Haap, M., Hetzel, J., & Riessen, R. (2014). Nasal high–flow oxygen therapy in patients with hypoxic respiratory failure: effect on functional and subjective respiratory parameters compared to conventional oxygen therapy and non-invasive ventilation (NIV). BMC anesthesiology, 14(1), 1-7.
Stéphan, F., Barrucand, B., Petit, P., Rézaiguia-Delclaux, S., Médard, A., Delannoy, B., ... & BiPOP Study Group. (2015). High-flow nasal oxygen vs noninvasive positive airway pressure in hypoxemic patients after cardiothoracic surgery: a randomized clinical trial. Jama, 313(23), 2331-2339.
Liesching, T. N., & Lei, Y. (2019). Efficacy of high-flow nasal cannula therapy in intensive care units: a meta-analysis of physiological and clinical outcomes. Journal of intensive care medicine, 34(2), 140-152.
Frat, J. P., Brugiere, B., Ragot, S., Chatellier, D., Veinstein, A., Goudet, V., ... & Girault, C. (2015). Sequential application of oxygen therapy via high-flow nasal cannula and noninvasive ventilation in acute respiratory failure: an observational pilot study. Respiratory care, 60(2), 170-178.
Simon, M., Braune, S., Frings, D., Wiontzek, A. K., Klose, H., & Kluge, S. (2014). High-flow nasal cannula oxygen versus non-invasive ventilation in patients with acute hypoxaemic respiratory failure undergoing flexible bronchoscopy-a prospective randomised trial. Critical Care, 18(6), 1-9.