Prevelance Of Prediabetes Among Rhematoid Arthritis Patients

Document Type : Original Article

Authors

Internal Medicine Department, Beni-Suef University

Abstract

Background : Rheumatoid Arthritis is a known risk factors for type 2 diabetes mellitus (T2DM). However, the relationship Rheumatoid Arthritis and prediabetes  is inconclusive. Objective: to explore the prevalence of prediabetes among rheumatoid arthritis in Egyptian population. Methods:  Fasting blood Sugar , 2 hour postprandial , HbA1c, Insulin level and HOMA-IR was measured in a group of 60 individuals , 30 patients with rheumatoid arthritis and 30 healthy controls to determine incidence of prediabetes among them . Patients were also exposed to careful history taking with special stress on history of any other autoimmune diseases or other comorbidities ,Height and weight were measured , Waist circumference (WC) was measured. ,   searched for Insulin resistance signs as acanthosis nigricans .Results: Our results showed that there was an association between Rheumatoid arthritis and prediabetes. The study illustrated that there was a statistical significant difference higher percentage of pre-diabetic patients among case group 29.2% versus 4.2% in control group with p-value 0.04 suggesting that  Rheumatoid arthritis has a role as a risk factor for developing both prediabetes and DM . Conclusion: Rheumatoid arthritis may be a risk factor for developing prediabetes in Egyptian patients.

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