Prognostic Value of Auditory Brainstem Evoked Response in Patients with Idiopathic Sudden Sensorineural hearing loss.

Document Type : Original Article

Authors

1 Audiovestibular department, Faculty of Medicine, Beni Suef University, Egypt

2 Otolaryngology department, Faculty of Medicine, Beni Suef University, Egypt

3 Minia General Hospital, Ministry of health, Egypt

Abstract

Background: A hearing loss of at least 30 decibels over three successive frequencies in less than 72 hours is referred to as idiopathic sudden sensorineural hearing loss (ISSNHL). Auditory brainstem response may serve as a potential prognostic indication in patients with ISSNHL, according to several studies. Low serum thyroid hormone levels can contribute to hearing loss since they are strongly tied to the cochlea's proper functioning. Aim: To investigate the prognostic value of ABR and the association between its results and the thyroid hormone serum levels in ISSNHL patients. Methods: Observational prospective study was conducted on thirty patients with ISSNHL that occurred within the last 72 h with 30 dB hearing loss at three sequential frequencies. Pure tone audiometry, word discrimination scores, immittencemetry and auditory brain stem response were performed on the day of admission then again on the third day after admission and one month later. Thyroid hormone serum level were assessed after admission. Result: Hearing recovery was observed in 21 patients (70%). The absolute latencies of waves I, III, and V latencies were statistically significantly delayed in the affected ears compared with the unaffected ears. There was a statistically significant correlation between hearing outcome and wave I latency. Wave V latency was statistically significantly negatively correlated with free T4. Conclusion: Auditory brainstem response is an important prognostic factor in ISSNHL but caution should    be considered when adopting ABR testing without assessing thyroid hormone levels.

Keywords

Main Subjects

References

  1. Marx M, Younes E, Chandrasekhar SS, et International consensus (ICON) on treatment of sudden sensorineural hearing loss. Eur Ann Otorhinolaryngol Head Neck Dis. 2018;135:S23- s28.
  2. Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery; Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Guideline of diagnosis and treatment of sudden deafness. Chin J Otorhinolaryngol Head Neck Surg. 2015;50:443e447.
  3. Heo, H. J., C. H. Choi, S. H. Hong, S. Kang, M. G. Kim, and Y. S. Chang. 2019. Is auditory brainstem response a prognostic factor in patients with sudden sensorineural hearing loss? Acta Otolaryngol 139 (11):1008-1013.
  4. Berker D, Karabulut H, Isik S, et Evaluation of hearing loss in patients with Graves' disease. Endocrine. 2012;41:116-121.
  5. O'Malley M R, Haynes D Sudden hearing loss Otolaryngol Clin North Am 20084103633–649.
  6. Bang, , H. Lee, H. Choi, D. Lee, Y. Kim, and D. K. Kim. 2019. Analysis of the relationship between changes in the auditory brainstem response and prognosis in patients with sudden hearing loss. J Laryngol Otol 133 (12):1103-1106.
  7. Seo, H.W.; Lee, S.Y.; Byun ; Lee, S.H.; Chung, J.H. Possible Existence of Cochlear Synaptopathy in Patients Completely Recovered from Idiopathic Sudden Sensorineural Hearing Loss. J. Clin Med. 2022, 11, 875.
  8. Lin, C., Y. C. Chou, C. H. Wang, L. W. Hung, C. P. Shih, B. H. Kang, W. Y. Yeh, and H. C. Chen. 2017. Correlation between auditory brainstem response and hearing prognosis in idiopathic sudden sensorineural hearing loss patients. Auris Nasus Larynx 44 (6):678-684.
  9. Zarandy M M, Ashtiani M T,Bastaninejad S, Satri S D, Nasirmohtaram S, and Ebrahimi N A Prognosticating hearing outcome in patients with idiopathic sudden sensorineural hearing loss by means of otoacoustic emissions and auditory brainstem response. Ear Nose Throat J 96 (12):E1- E5.
  10. Chandrasekhar, , V. Kowsalya, and B. Vijayalakshmi. 2011. Electrophysiological changes on brainstem auditory evoked potentials in hypothyroid patients. J Pharm Res 4:2856-2859.
  11. Anjana, , N. Vaney, O. P. Tandon, and S. V. Madhu. 2006. Functional status of auditory pathways in hypothyroidism: evoked potential study. Indian J Physiol Pharmacol 50 (4):341-349.
  12. Thornton A, Jarvis Auditory brainstem response findings in hypothyroid and hyperthyroid disease. Clin Neurophysiol. 2008;119(4):786–790.
Egyptian Journal of Medical Research
Volume 4, Issue 4
October 2023
Pages 145-155

Files

Share

How to cite

Statistics