Cognitive Impairment In Patients With Chronic Liver Diseases

Document Type : Original Article

Authors

1 Department of Gastroenterology, Hepatology and infectious diseases, Faculty of Medicine, Beni-Suef University, Egypt

2 Psychiatric Department, Faculty of Medicine, Beni-Suef University, Egypt

10.21608/ejmr.2023.194577.1347

Abstract

Background and Aims: The aim of the study is assessment of cognitive functions in patients with chronic liver diseases (CLD) of various etiologies.  Patients and methods; One hundred and twenty patients diagnosed with CLD of various etiologies were evaluated at the Hepatology and Gastroenterology clinics, at Beni-Suef University Hospital. They were recruited from November 2021 to April 2022. The Mini-mental state examination and Wechsler Adult Intelligence State score-4 were used to assess cognitive functions in the study group. Results:   Out of one hundred and twenty patients (60 males and 60 females), 15 patients (12. 5%) of the study group showed cognitive dysfunction and 105 patients (87.5%) had normal cognitive function by Mini-Mental State Examination (MMSE). Whereas, 33 patients (27.5%) had cognitive impairment and 53 patients (44.2%) had attention and memory dysfunction detected by applying the Wechsler adult intelligence scale -4 (WAIS- 4 ). Conclusion: Based on the findings, the study concluded that patients with CLD have cognitive impairment in the form of dysfunction of (cognition, attention, memory, and executive functions)

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