Posterior Pharyngeal Wall Augmentation with Fat Graft in Patients having Mild Velopharyngeal Insufficiency

Document Type : Original Article

Authors

1 Otorhinolaryngology department, Faculty of Medicine, Beni-Suef University, Beni-Suef 62511, Egypt

2 Otorhinolaryngology department, Beni-Suef Specialized hospital, Beni-Suef 62511, Egypt

3 Phoniatrics department, Faculty of Medicine, Beni-Suef University, Beni-Suef 62511, Egypt

Abstract

Background: The velopharynx functional and structural integrity is essential for the production of normal speech resonance. The velopharynx is a dynamic and intricate structure that serves as a barrier between the oral and nasal cavities through the production of sound. Hyper-nasality, nasal escape, and compensatory errors are all consequences of anatomical abnormalities of the velopharyngeal (VP) valve (VP in-sufficiency = VPI), which collectively diminish speech intelligibility.  Aim of the Work: To assess the outcome and the posterior pharyngeal wall augmentation complications the with fat graft in patients having mild VP insufficiency. Patients and Methods: A single-arm clinical trial was conducted on 20 patients with mild VPI. They were treated with the posterior pharyngeal wall augmentation with autologous fat injection at a tertiary hospital. The study started from December 2022 till March 2024.  Results: There was a significant development in the open nasality degree, consonants imprecision, audible nasal air emission, overall intelligibility, facial grimace, closure of the gap, distorted vowels, A/E and Cold Mirror tests after the operation in seventeen patients, and three patients did not improve. All patients did not have any complications from the operation. Conclusion: Our study reported that augmenting the posterior pharyngeal wall with fat graft is effective in the management of hypernasality in mild VP gap patients. This method has a minimal complication rate due to autologous tissue application.

Keywords

Main Subjects


  1. Nam, M. (2018): Surgical treatment of velopharyngeal insufficiency. Archives of Craniofacial Surgery, 19(3), 163-178.
  2. Panizza, R., Ghiglione, M., Zingarelli, M., Massa, M., Carlini, C., Arnoldi, R., Prato, P., Scarrone, S. & Vaccarella, F. (2018): Autologous fat grafting in the treatment of velopharyngeal insufficiency: Clinical outcomes and treatment tolerability survey in a case series of 21 patients. Indian journal of plastic surgery: official publication of the Association of Plastic Surgeons of India, 51(2), 145–154.
  3. Sweeney, M., Lanier, T., Purnell, A. & Gosain, K. (2015): Genetics of cleft palate and velopharyngeal insufficiency. Journal of pediatric genetics, 4(01), 9-16.
  4. Perez, F. & Brigger, T. (2015): Posterior pharyngeal wall augmentation’, in Surgery for Pediatric Velopharyngeal Insufficiency. Karger Publishers, 74-80.
  5. Raposo-Amaral, A., Monte, M. & Raposo-Amaral, E. (2023): Treatment of Velopharyngeal Insufficiency via Bilateral Myomucosal Buccinator Flaps. Plastic and Reconstructive Surgery, 1084-1097.
  6. Gardiol, S. (1984): The Problem of the Dyslexic Child in a Foreign Language Programme. The International Schools Journal, 1, 68-76.
  7. Khafagy, G., Kassamy, H. & Mohamed, A. (2021): Augmentation of the posterior pharyngeal wall with autologous tragal cartilage for management of velopharyngeal valve insufficiency in adults. Auris Nasus Larynx, 48, 428-33.
  8. Abdali, H. & Yaribakht, M. (2019): Assessment of outcomes and complications of posterior pharyngeal wall augmentation with dermal fat graft in patients with Velopharyngeal Insufficiency (VPI) after primary cleft palate repair: A pilot study. JPRAS open, 19, 6-18.
  9. Lau, D., Oppenheimer, J., Buchman, R., Berger, M. & Kasten, J. (2013): Posterior pharyngeal fat grafting for velopharyngeal insufficiency. Cleft Palate Craniofac J, 50, 51-8.
  10. Lypka, M., Bidros, R., Rizvi, M., Gaon, M., Rubenstein, A., Fox, D. & Cronin, E. (2010): Posterior pharyngeal augmentation in the treatment of velopharyngeal insufficiency: a 40-year experience. Annals of plastic surgery, 65(1), 48-51.
  11. Denny, D., Marks, M. & Oliff-Carneol, S. (1993): Correction of velopharyngeal insufficiency by pharyngeal augmentation using autologous cartilage: a preliminary report. Cleft Palate Craniofac J, 30, 46-54.
  12. Trigos, I., Ysunza, A., Gonzalez, A. & Vazquez, M. (1988): Surgical treatment of borderline velopharyngeal insufficiency using homologous cartilage implantation with videonasopharyngoscopic monitoring. Cleft Palate Craniofac J, 25, 167-70.
  13. Orr, C., Levine, S. & Buchanan, T. (1987): Effect of cleft palate repair and pharyngeal flap surgery on upper airway obstruction during sleep. Plast Reconst Surg, 80, 226-30.
  14. Sirois, M., Caouette-Laberge, L., Spier, S., Larocque, Y. & Egerszegi, P. (1994): Sleep apnea following a pharyngeal flap: a feared complication. Plast Reconst Surg, 93, 943-7.
  15. Witt, D. (2022): Sphincter Pharyngoplasty. In Surgical Atlas of Cleft Palate and Palatal Fistulae. Singapore: Springer Nature Singapore, 21, 393-401.
  16. Williams, W., Eisenbach, C. & Bzoch, K. (1982): A long term study on treating velopharyngeal insufficiency by Teflon injection. Cleft Palate Craniofac J, 19, 47-56.
  17. Quoc, H., Taupin, T., Guérin, N. & Delay, E. (2015): Volumetric evaluation of fat resorption after breast lipofilling. Annales de Chirurgie Plastique Esthétique. Elsevier, 495-499.
  18. Teixeira, P., Reid, A. & Greensmith, A. (2011): Fatty hypertrophy cause obstructive sleep apnea after fat injection for velopharyngeal incompetence. The Cleft palate-craniofacial journal, 48, 473-477.